Archive for October 2010
Cell based reporter assays: misleading approach in drug discovery?
Posted by: sciclips on: October 25, 2010
Cell based reporter and in vitro homogeneous assays that are used in drug/drug target screening are considered to be powerful and convenient tools in primary screening of compounds or drug molecules. Research reagent and pharmaceutical/biotechnology companies are heavily involved in developing new technologies and methods for primary screening using homogeneous or cell based reporter assays. [...]
Are large protein fusion tag based technologies, including protein arrays, truly useful in functional proteomics or systems biology or drug discovery research?
Posted by: sciclips on: October 5, 2010
- In: Proteomics
- 3 Comments
There are several technologies developed for studying protein-protein interactions and several products available in the market using some of these technologies. These technologies include tandem affinity purification and protein microarray based methods/kits for functional proteomics and system biology applications. These technologies look very promising and elegant. However, careful scientific analysis of these technologies raises some [...]
Open innovation: an answer for neglected diseases
Posted by: sciclips on: October 3, 2010
Read the article (Opinion) from SciClips published in Future Medicinal Chemistry (September 2010, Vol. 2, No. 9, Pages 1411-1415) First paragraph “In 2003, Henry Chesbrough, a professor and executive director at the Center for Open Innovation at University of California Berkeley (UC Berkeley), first coined the term ‘open innovation’, in his book Open Innovation: The [...]
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