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Posts Tagged ‘oncology biomarker database

Therapeutic Drug Target Database: Contains more than 6000 therapeutic drug targets extracted from patents and patent applications.


Novel/Potential Drug Target Database: Contains more than 3000 therapeutic drug targets extracted from journal articles.


Combination Therapy Database: Contains combination therapy methods for more than 1300 diseases (extracted from journal articles, patents and clinical trials).


Therapeutic and Experimental Drug Database: Contains more that 14,000 drugs extracted from patents and patent applications.


Cancer Biomarker Database: A comprehensive oncology biomarker database with companion diagnostics pathway analysis.


Bioprotocols Database: A unique list of bioprotocols linked to published journal articles and patents.



Drug Discovery News: Latest drug discovery news from patents and patent applications.



Sciclips Blog: Blogs on drug discovery, stem cells, proteomics, biomarkers and open innovation.




Related blogs:

1. Cell Based Reporter Assays vs. Animal Studies in Drug Discovery- Potential Limitations, Risks and Liabilities
2. Cell based reporter assays: misleading approach in drug discovery?
3. Cancer Theranostics – Potential Applications of Cancer Biomarker Database
2. Are stem cells ready as a next generation drug discovery tool?


A comprehensive oncology biomarker database with cancer companion diagnostic biomarker pathway maps (theranostic biomarkers)

With the growing trend of personalized healthcare concept and advancement in biomarker research, there is a need for a comprehensive cancer biomarker database that can help in finding new diagnostic, prognostic and companion diagnostic biomarkers. Future success in developing innovative personalized cancer drugs lies in adopting new differential diagnostic procedures along with companion biomarker assays to identify the most appropriate cancer patient, tumor type and disease state.

Sciclips has launched a comprehensive diagnostic and prognostic cancer biomarker database with cancer companion diagnostics biomarker pathway maps. This database contains more than 8500 discovery phase or preclinical or clinical cancer biomarkers that were identified or validated using patient derived samples. This database covers a wide variety of biomarkers such as blood cancer biomarkers (peripheral blood, plasma, serum etc), tumor biomarkers, urinary cancer biomarkers, fecal cancer biomarkers, saliva cancer biomarkers, breath cancer biomarkers etc.

Our cancer biomarker database contains biomarkers for more than 100 types of cancer. For each cancer type, the biomarkers are classified into 1) diagnostic biomarkers: for the diagnostics application, 2) disease predictive/risk assessment biomarkers: for predicting the risk or genetic susceptibility in developing cancer, 3) drug efficacy/response biomarkers: biomarkers for studying the efficacy of anti-cancer drug treatments, including predictive biomarkers and 4) prognostic biomarkers: for determining the clinical outcome in cancer patients. The types of cancer biomarkers include protein biomarkers, miRNA biomarkers, SNP biomarkers, Gene expression biomarkers, epigenetic biomarkers and metabolomic biomarkers. Patient/sample details, experimental results/observations, biological and molecular functional analysis, biological process analysis, protein-protein interaction networks of each biomarker are listed in this database.This database will be a useful tool for the discovery of new cancer biomarkers as well as clinical validation of biomarkers.

The cancer companion diagnostics biomarker pathway database is an innovative database of protein-protein interactions networks of cancer drug efficacy/response/predictive biomarkers. A model pathway from the database is shown in Fig.1. This pathway maps can be useful in identifying new anti-cancer drug predictive and response biomarkers, including theranostic biomarkers, for the discovery of new drug targets with improved efficacy or targeted therapy to overcome side effects, patient stratification, developing personalized strategies for monitoring cancer progression, treatment, diagnosis and prognosis.

Please follow this link to view the database (preview is available): Details: http://www.sciclips.com/sciclips/diagnostic-prognostic-cancer-biomarker-main.do


Fig.1: Companion diagnostics pathway analysis of biomarkers associated with doxorubicin cardiotoxicity in childhood acute lymphoblastic leukemia (ALL)- please see the database for more details.

Related blog:

1. Strategies for Rational and Personalized Cancer Biomarker Discovery

2. Cancer Theranostics – Potential Applications of Cancer Biomarker Database


Comprehensive Cancer Bomarker Database

Sciclips consultancy

Diagnostic & Prognostic Biomarker Database

Bioprotocol database (open access)

Combination therapy database (open access)

Therapeutic drug target database (open access)

Bioinformatics databases (open access)

Stem cell researchers database

A comprehensive database for stem cell researchers, Stem cell research reagents, Stem cell patents, Stem cell grants, Stem cell clinical trials, Stem cell statistics, Stem cell news and Stem cell open innovation ideas. Please visit http://www.sciclips.com/

Sciclips consultancy

Proteomics researchers database

A comprehensive database for proteomics researchers, Proteomics research reagents, Proteomics patents, Proteomics grants, Proteomics clinical trials, Proteomics statistics, Proteomics news and Proteomics open innovation ideas. Please visit http://www.sciclips.com/

Share or sell research reagents prepared in your laboratory

Drug target database (open access)

Pharmacogenomics protocols online

Proteomics and Mass spectrometry (MS) protocols online

Therapeutic drug targets database (open access)

Drug discovery, Biopharmaceuticals, HTS assays protocols online

Protein display/Protein engineering/Directed evolution protocols online

Molecular biology and Cell biology protocols online

siRNA protocols miRNA protocols online

Video protocols

Cell culture video protocols, Cytotoxicity assay video protocols, Stem cell video protocols, Molecular biology video protocols http://www.sciclips.com/sciclips/video-protocols.do

Sciclips consultancy

Sciclips

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Bioprotocols online (open access)

Combination therapy database (open access)

Therapeutic drug targets database (open access)

Bioinformatics databases (open access)

HTS assay protocols online (open access)

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