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Posts Tagged ‘VDAC1_Parkinson’s disease

Following are the highlights of recent US patent applications on drug discovery. Details of each patent application with link to respective patents are available in the website.

1. Irreversible inhibitors of Bruton’s tyrosine kinase (Btk) for treating rheumatoid arthritis and asthma
2. Apple polyphenols as inhibitors of lectin-like oxidized LDL receptor for treating arteriosclerosis
3. Treating Alzheimer’s disease using hydroxychavicol isolated from Piper Betel
4. Panduratin derivative extracted from Boesenbergia pandurata for treating metabolic diseases
5. Jasmonic acid compound for treating greasy skin
7. Citrulline for treating aneurysmal subarachnoid hemorrhage
8. Modified amino acids as inhibitors of blood platelet aggregation
10. Halogenated prostaglandin analogs for treating constipation
12. Doxepin for treating insomnia in elderly patients
13. Taxol for treating atherosclerosis and restenosis
14. MicroRNA’s as therapeutic drug targets of head and neck cancer
15. IL-4R alpha antisense oligonucleotide therapy for asthma and allergic rhinitis
16. MicroRNAs as therapeutic drug targets for treating viral infections
17. Gadd45 as a therapeutic target of mood disorders
18. MicroRNAs as therapeutic drug targets of acute myeloid leukemia
19. T type calcium channel inhibitors for the treatment of cancer
20. Human type 2 taste receptor 8 (hT2R8) antagonists as bitter taste blockers
21. One day treatment with famciclovir for recurrent herpes labialis
22. BEC1 potassium channel inhibitor for treating attention deficit/hyperactivity disorder
23. Combination therapy for treating Charcot-Marie-Tooth disease
24. Tetracycline for treating meibomian gland disease
25. Voltage-dependent anion channel 1 (VDAC1) protein as a therapeutic drug target of Parkinson’s disease

Details: http://www.sciclips.com/sciclips/drug-discovery-news.do

Related blogs:

1. Cell Based Reporter Assays vs. Animal Studies in Drug Discovery- Potential Limitations, Risks and Liabilities
2. Cell based reporter assays: misleading approach in drug discovery?
3. Cancer Theranostics – Potential Applications of Cancer Biomarker Database
4. Are stem cells ready as a next generation drug discovery tool?

Related tools:

1. Comprehensive cancer biomarker database with companion diagnostics pathway
2. Bioprotocols- for Advanced Researchers
4. Biomarker news


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