Sciclips's Blog

Recent Drug Discovery Patents (US patents issued)

Posted on: September 1, 2011


Highlights of recent drug discovery patents (US issued) on August 30, 2011:

1. Combination therapy using activin-ActRII antagonists for the treatment of anemia
2. Nerve growth factor (NGF) as a drug target for the treatment of bone cancer pain
3. Calcitonin gene-related peptide (CGRP) as a drug target for the treatment of headaches
4. Tumor necrosis factor (TNF) pathway as a drug target for the treatment of polycystic kidney disease (PKD)
5. Combination therapy for cancer using toxin-defective Clostridium spore and a microtubule stabilizing anti-tumor agent
6. Junctional adhesion molecule-C (JAM-C) as a drug target for the treatment of glioma
7. Chitosan nanoparticles for oral drug delivery
8. Sorcin based gene therapy for the treatment of heart failure
9. GP88 as a drug target for inhibiting the growth of hematopoietic malignant cells
10. HSP27 phosphorylation as a drug target for the treatment of blistering disorder
11. Indazoles as antagonists of CCR1 for the treatment of rheumatoid arthritis and multiple sclerosis
12. Combination therapy for treatment of cancer
13. Combination of IDO inhibitor and chemotherapeutic agent for the treatment of cancer
14. NKCC1 cotransporter inhibitors for the treatment of neuropsychiatric disorders
15. Dopa decarboxylase inhibitor droxidopa for the treatment of fibromyalgia
16. Heteroaryl based inhibitors of Nedd8-activating enzyme for the treatment of cancer
17. Trace amine associated receptor1 (TAAR1) ligands for the treatment of CNS disorders
18. Irreversible inhibitors of Bruton’s tyrosine kinase (Btk)
19. Benzylether and benzylamino beta-secretase inhibitors for the treatment of Alzheimer’s disease
20. Novel substituted pyrazolopyridines based kinase inhibitors for the treatment of cancer
21. Inhibitors of plasma carboxypeptidase B for the treatment and prevention of thrombosis
22. Single dose aromatase inhibitor for treating infertility
23. New aldosterone synthase inhibitors for the treatment of high blood pressure
24. Selective androgen receptor modulators for the treatment of muscle wasting
25. Histone deacetylase (HDAC) inhibitors for the treatment of neurodegenerative diseases and human spinal muscular atrophy
26. Substituted phenoxyacetic acids that are active at the CRTh2 receptor for the treatment of asthma and COPD
27. Human growth hormone derived peptides for the treatment of bone disorders
28. Adenovirus protein to increase insulin sensitivity and ameliorate diabetes
29. STEAP-1 protein as a cancer drug target
30. Anti-PD-1 antibodies for the treatment of cancer
31. Therapeutic drug target for the treatment of congenital hydrocephalus
32. Hairless protein as a drug target for hair removal
33. Soluble epoxide hydrolase inihitors and its applications
34. Soluble amide and ester pyrazinoylguanidine sodium channel blockers for the treatment of cardiovascular diseases
35. Novel 1,2-dihydroquinoline derivatives as glucocorticoid receptor modulators
36. Compounds that inhibit the IgE receptor signaling cascade that leads to the release of chemical mediators
37. FXR modulators for the treatment of non-insulin dependent diabetes mellitus
38. Compound having a beta 3 adrenergic receptor agonist activity for the treatment of overactive bladder and urinary incontinence
39. Low molecular weight synthetic modulators of 14273 receptor (GPR120) for the treatment of diabetes

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