Sciclips's Blog

Archive for April 2012


We have launched an open access stem cell therapy database that contains comprehensive information on the therapeutic applications of stem cells for more than 300 diseases or disorders. The data was extracted from patents, patent applications and clinical trials. Highlights of the key invention and protocols/methods used for validating the therapeutic applications of various stem cell types are also included in this database. Link to the database: http://www.sciclips.com/sciclips/stem-cell-therapeutics-database-main.do

Related tools:

1. Stem Cell Protocols
2. Therapeutic and Experimental Drugs Database
3. Comprehensive cancer biomarker database with companion diagnostics pathway

Related blogs:

1. Cell Based Reporter Assays vs. Animal Studies in Drug Discovery- Potential Limitations, Risks and Liabilities
2. Cell based reporter assays: misleading approach in drug discovery?
3. Cancer Theranostics – Potential Applications of Cancer Biomarker Database
4. Are stem cells ready as a next generation drug discovery tool?


Highlights of recent US patent applications on protein biomarkers and molecular diagnostics.

1. Biomarker for monitoring the efficacy of aspirin treatment
2. Biomarker for predicting the efficacy of trental (pentoxifylline) therapy in transitory ischemic attacks (TIA)/stroke patients
3. Biomarker for identifying infants with congenial heart diseases requiring cardiac surgery
4. Versican as a biomarker of renal injury
5. Fecal microRNA (miRNA) biomarkers for the detection of hereditary colorectal cancers
6. Real-time PCR method for the detection of Clostridium botulinum
7. Biomarkers for diagnosing susceptibility to insulin resistance in Hispanic Americans
8. Biomarkers for predicting response to antibody therapy in rheumatoid arthritis patients
9. Biomarkers for the detection of vasculitis in Wegener’s granulomatosis, microscopic polyangiitis and Horton’s disease
10. Immunodiagnostic biomarker for the sero-detection of Anaplasma phagocytophilum
11. Peptide biomarkers for the diagnosis of rheumatoid arthritis
12. Urinary biomarker for diagnosing HIV associated nephropathy (HIVAN)
Details: http://www.sciclips.com/sciclips/biomarker-news.do

Related tools:
1. Comprehensive cancer biomarker database with companion diagnostics pathway
2. Bioprotocols
3. Drug discovery news
4. Biomarker news

Related blogs:

Strategies for Rational and Personalized Cancer Biomarker Discovery

1. Cancer Theranostics – Potential Applications of Cancer Biomarker Database

Following are the highlights of recent US patent applications on drug discovery. Details of each patent application with link to respective patents are available in the website.

1. Irreversible inhibitors of Bruton’s tyrosine kinase (Btk) for treating rheumatoid arthritis and asthma
2. Apple polyphenols as inhibitors of lectin-like oxidized LDL receptor for treating arteriosclerosis
3. Treating Alzheimer’s disease using hydroxychavicol isolated from Piper Betel
4. Panduratin derivative extracted from Boesenbergia pandurata for treating metabolic diseases
5. Jasmonic acid compound for treating greasy skin
7. Citrulline for treating aneurysmal subarachnoid hemorrhage
8. Modified amino acids as inhibitors of blood platelet aggregation
10. Halogenated prostaglandin analogs for treating constipation
12. Doxepin for treating insomnia in elderly patients
13. Taxol for treating atherosclerosis and restenosis
14. MicroRNA’s as therapeutic drug targets of head and neck cancer
15. IL-4R alpha antisense oligonucleotide therapy for asthma and allergic rhinitis
16. MicroRNAs as therapeutic drug targets for treating viral infections
17. Gadd45 as a therapeutic target of mood disorders
18. MicroRNAs as therapeutic drug targets of acute myeloid leukemia
19. T type calcium channel inhibitors for the treatment of cancer
20. Human type 2 taste receptor 8 (hT2R8) antagonists as bitter taste blockers
21. One day treatment with famciclovir for recurrent herpes labialis
22. BEC1 potassium channel inhibitor for treating attention deficit/hyperactivity disorder
23. Combination therapy for treating Charcot-Marie-Tooth disease
24. Tetracycline for treating meibomian gland disease
25. Voltage-dependent anion channel 1 (VDAC1) protein as a therapeutic drug target of Parkinson’s disease

Details: http://www.sciclips.com/sciclips/drug-discovery-news.do

Related blogs:

1. Cell Based Reporter Assays vs. Animal Studies in Drug Discovery- Potential Limitations, Risks and Liabilities
2. Cell based reporter assays: misleading approach in drug discovery?
3. Cancer Theranostics – Potential Applications of Cancer Biomarker Database
4. Are stem cells ready as a next generation drug discovery tool?

Related tools:

1. Comprehensive cancer biomarker database with companion diagnostics pathway
2. Bioprotocols- for Advanced Researchers
4. Biomarker news

Therapeutic Drug Target Database: Contains more than 6000 therapeutic drug targets extracted from patents and patent applications.


Novel/Potential Drug Target Database: Contains more than 3000 therapeutic drug targets extracted from journal articles.


Combination Therapy Database: Contains combination therapy methods for more than 1300 diseases (extracted from journal articles, patents and clinical trials).


Therapeutic and Experimental Drug Database: Contains more that 14,000 drugs extracted from patents and patent applications.


Cancer Biomarker Database: A comprehensive oncology biomarker database with companion diagnostics pathway analysis.


Bioprotocols Database: A unique list of bioprotocols linked to published journal articles and patents.



Drug Discovery News: Latest drug discovery news from patents and patent applications.



Sciclips Blog: Blogs on drug discovery, stem cells, proteomics, biomarkers and open innovation.




Related blogs:

1. Cell Based Reporter Assays vs. Animal Studies in Drug Discovery- Potential Limitations, Risks and Liabilities
2. Cell based reporter assays: misleading approach in drug discovery?
3. Cancer Theranostics – Potential Applications of Cancer Biomarker Database
2. Are stem cells ready as a next generation drug discovery tool?


Comprehensive Cancer Bomarker Database

Sciclips consultancy

Diagnostic & Prognostic Biomarker Database

Bioprotocol database (open access)

Combination therapy database (open access)

Therapeutic drug target database (open access)

Bioinformatics databases (open access)

Stem cell researchers database

A comprehensive database for stem cell researchers, Stem cell research reagents, Stem cell patents, Stem cell grants, Stem cell clinical trials, Stem cell statistics, Stem cell news and Stem cell open innovation ideas. Please visit http://www.sciclips.com/

Sciclips consultancy

Proteomics researchers database

A comprehensive database for proteomics researchers, Proteomics research reagents, Proteomics patents, Proteomics grants, Proteomics clinical trials, Proteomics statistics, Proteomics news and Proteomics open innovation ideas. Please visit http://www.sciclips.com/

Share or sell research reagents prepared in your laboratory

Drug target database (open access)

Pharmacogenomics protocols online

Proteomics and Mass spectrometry (MS) protocols online

Therapeutic drug targets database (open access)

Drug discovery, Biopharmaceuticals, HTS assays protocols online

Protein display/Protein engineering/Directed evolution protocols online

Molecular biology and Cell biology protocols online

siRNA protocols miRNA protocols online

Video protocols

Cell culture video protocols, Cytotoxicity assay video protocols, Stem cell video protocols, Molecular biology video protocols http://www.sciclips.com/sciclips/video-protocols.do

Sciclips consultancy

Sciclips

Bioprotocols online (open access)

Combination therapy database (open access)

Therapeutic drug targets database (open access)

Bioinformatics databases (open access)

HTS assay protocols online (open access)