Sciclips's Blog

Potential Use of Drug Response-Efficacy Biomarkers for Predicting Life-Threatening Disease Causing Side Effects of Therapeutic Drugs

Posted on: September 4, 2012


This scientific blog analyzes potential applications of drug response-efficacy biomarkers for predicting future onset of drug therapy induced life-threatening diseases, such as cardiovascular diseases, infectious diseases and cancer. Enabling applications of drug response-efficacy biomarkers for predicting drug-induced side effects may lead to the development of “smart biomarkers”, which can reduce morbidity and mortality in patients, and can revolutionize personalized medicine approaches. In order to achieve this goal, we proposed a model for the discovery of drug response-efficacy biomarkers and the translational utilization of these biomarkers for personalized therapies. In an exploratory analysis, anti-TNF therapy response markers of rheumatoid arthritis (RA) were analyzed, by intelligent data mining and data analysis, to demonstrate that these biomarkers may be potentially used for predicting the risk in developing cardiovascular diseases (CVDs), like atherosclerosis, in RA patients. Please follow this link to read the blog: http://www.sciclips.com/sciclips/blogArticle.do?id=Potential Use of Drug Response-Efficacy Biomarkers for Predicting Life-Threatening Disease Causing Side Effects of Therapeutic Drugs

Related tools:
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1. Cancer Theranostics – Potential Applications of Cancer Biomarker Database

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