Recent Patent Applications in Anti-Cancer Drug Discovery

Posted by: sciclips on: September 19, 2011

• In: Drug discovery
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Highlights of recent US patent applications published on September 15, 2011:

1. Anti-KAAG1 monoclonal antibodies for the treatment of ovarian cancer
2.Novel inhibitors of cdc25 phosphatases for the treatment of cancer
3. Double stranded iRNA mediated inhibition of VEGF
4. Alpha-fetoprotein (AFP) antibodies for treating hepatocellular carcinoma and germ cell tumors
5. MicroRNA, miR-101, as a target for cancer therapy
6. Treating radiation damage using genetically modified mesenchymal stem cells
7. Novel compounds that inhibit MDM2-p53 interaction for the treatment of cancer
8. Allopurinol for the treatment or prevention of chemotherapy-induced palmar plantar erythrodysesthesia (PPE)
9. Cyclin-dependent kinase (CDK) inhibitors to reduce the cytotoxicity of chemotherapeutic compounds in cancer patients
10. Cyclin-dependent kinase (CDK) inhibitors to reduce the side effects of radiation therapy in cancer patients
11. A method for optimizing treatment of chronic myeloid leukemia (CML) with imatinib mesylate
12. Bidesmosidic betulin and betulinic acid saponin derivatives for the treatment of lung, colorectal, breast and prostate cancers
13. Polymer micelle composition for the treatment of resistant cancers
14. Combination of pterostilbene and quercetin for the treatment of melanoma
15. Orally bioavailable compounds for treating cancer
16. TRIM71 as a therapeutic drug target of ovarian, lung and kidney cancers
17. MicroRNAs as therapeutic drug targets for the treatment of malignant peripheral nerve sheath tumors (MPNST)
18. PTH/PTHrP receptors as therapeutic drug target for the treatment of leukemia
19. Treating hormone refractory prostate cancer using compounds that increase in intracellular granularity of cancer cells
20. Combination of EGFR tyrosine kinase inhibitor and curcumin for treating non-small cell lung cancer
21. Thrombin inhibitors for treating a prevascularized metastasized tumor

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Tags: Anti-cancer drug discovery patents, chronic myeloid leukemia treatment, germ cell tumor drug target, hepatocellular carcinoma drug target, hormone refractory prostate cancer drug discovery, kidney cancer drug target, leukemia drug target, lung cancer drug target, malignant peripheral nerve sheath tumors drug target, oral cancer drug, ovarian cancer drug target, treatment of resistant cancers